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Evangelos J Giamarellos-Bourboulis Selected Research

Disease Progression

2/2023Efficacy and safety of early soluble urokinase plasminogen receptor plasma-guided anakinra treatment of COVID-19 pneumonia: A subgroup analysis of the SAVE-MORE randomised trial.
1/2023Anakinra in hospitalized COVID-19 patients guided by baseline soluble urokinase plasminogen receptor plasma levels: A real world, retrospective cohort study.
1/2022ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically lll COVID-19 Patients.
10/2021Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial.
1/2010Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.

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Evangelos J Giamarellos-Bourboulis Research Topics

Disease

112Sepsis (Septicemia)
01/2024 - 09/2002
80Infections
01/2024 - 03/2002
49COVID-19
04/2024 - 01/2020
26Pneumonia (Pneumonitis)
03/2024 - 11/2008
25Necrosis
12/2021 - 10/2004
24Inflammation (Inflammations)
04/2024 - 05/2002
23Septic Shock (Toxic Shock Syndrome)
01/2023 - 09/2002
22Critical Illness (Critically Ill)
07/2023 - 09/2002
20Hidradenitis Suppurativa
04/2024 - 06/2010
17Ventilator-Associated Pneumonia
01/2022 - 01/2008
13Pyelonephritis
01/2022 - 01/2004
12Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
01/2024 - 09/2002
11Respiratory Insufficiency (Respiratory Failure)
03/2024 - 01/2020
11Shock
01/2023 - 10/2006
9Multiple Organ Failure (MODS)
01/2022 - 09/2002
7Lymphopenia (Lymphocytopenia)
07/2023 - 12/2010
7Wounds and Injuries (Trauma)
01/2022 - 05/2005
6Neoplasms (Cancer)
07/2023 - 05/2004
6Communicable Diseases (Infectious Diseases)
05/2023 - 10/2012
6Bacterial Infections (Bacterial Infection)
01/2023 - 01/2011
6Coinfection
03/2022 - 12/2020
5Disease Progression
02/2023 - 01/2010
5Bacteremia
01/2023 - 01/2017
5Pancreatitis
01/2021 - 05/2002
5Osteomyelitis
01/2020 - 07/2008
5Multiple Trauma (Multiple Injuries)
01/2020 - 05/2005
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
04/2024 - 06/2006
4Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2024 - 01/2017
4Intraabdominal Infections
01/2022 - 01/2010
4Urinary Tract Infections (Urinary Tract Infection)
01/2022 - 12/2015
4Fever (Fevers)
01/2019 - 01/2008
4Peritonitis
06/2013 - 03/2003
4Hemorrhagic Shock
01/2011 - 10/2006
3Body Weight (Weight, Body)
01/2023 - 08/2003
3Pain (Aches)
01/2023 - 01/2014
3Abscess
01/2023 - 02/2015

Drug/Important Bio-Agent (IBA)

34Biomarkers (Surrogate Marker)IBA
04/2024 - 04/2011
28CytokinesIBA
01/2023 - 10/2006
25Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2024 - 08/2003
22Interleukin-6 (Interleukin 6)IBA
11/2023 - 08/2003
21Clarithromycin (Biaxin)FDA LinkGeneric
02/2024 - 01/2004
18Anti-Bacterial Agents (Antibiotics)IBA
01/2024 - 06/2009
18InterleukinsIBA
09/2023 - 09/2006
14Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
03/2024 - 01/2016
13Urokinase Plasminogen Activator ReceptorsIBA
03/2024 - 11/2011
13ProcalcitoninIBA
01/2024 - 09/2002
13C-Reactive ProteinIBA
12/2023 - 10/2009
12EndotoxinsIBA
11/2021 - 01/2003
10MacrolidesIBA
01/2024 - 01/2008
10Interleukin-10 (Interleukin 10)IBA
10/2021 - 02/2006
10Angiopoietin-2IBA
10/2021 - 11/2008
9Adalimumab (Humira)FDA Link
04/2024 - 08/2016
9Triggering Receptor Expressed on Myeloid Cells-1IBA
10/2021 - 01/2006
8Ferritins (Ferritin)IBA
07/2023 - 01/2019
8InterferonsIBA
01/2023 - 12/2009
8Immunologic Factors (Immunomodulators)IBA
11/2021 - 02/2005
8Interleukin-8 (Interleukin 8)IBA
01/2017 - 01/2006
8Malondialdehyde (Propanedial)IBA
07/2013 - 01/2004
7HLA-DR Antigens (HLA-DR)IBA
07/2023 - 01/2010
7EnzymesIBA
01/2023 - 01/2007
7Interferon-gamma (Interferon, gamma)IBA
01/2023 - 12/2008
7Colistin (Coly-Mycin)FDA Link
09/2021 - 11/2002
7salicylhydroxamic acid (SHAM)IBA
01/2020 - 07/2008
7LipopolysaccharidesIBA
01/2017 - 04/2011
6VaccinesIBA
11/2023 - 01/2020
6Hydrocortisone (Cortisol)FDA LinkGeneric
05/2023 - 01/2010
6Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
02/2023 - 01/2020
6Immunoglobulins (Immunoglobulin)IBA
01/2021 - 12/2007
6Moxifloxacin (Avelox)FDA Link
08/2017 - 06/2008
6Amikacin (A.M.K)FDA LinkGeneric
09/2015 - 02/2004
5RNA (Ribonucleic Acid)IBA
03/2024 - 06/2009
5Interleukin-17 (Interleukin 17)IBA
11/2023 - 08/2013
5Proteins (Proteins, Gene)FDA Link
10/2023 - 01/2016
5CreatinineIBA
01/2022 - 07/2008
5Antigen-Antibody Complex (Immune Complex)IBA
01/2022 - 02/2015
5Immunoglobulin M (IgM)IBA
01/2021 - 09/2012
4LigandsIBA
05/2023 - 06/2009
4PlasminogenIBA
02/2023 - 10/2021
4Rifampin (Rifampicin)FDA LinkGeneric
02/2023 - 01/2007
4Adrenal Cortex Hormones (Corticosteroids)IBA
01/2023 - 01/2010
4Dexamethasone (Maxidex)FDA LinkGeneric
01/2023 - 01/2013
4AntibodiesIBA
01/2022 - 11/2008
4DNA (Deoxyribonucleic Acid)IBA
02/2018 - 03/2012
4InflammasomesIBA
01/2017 - 11/2010
4Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
08/2010 - 05/2004
3human AZU1 proteinIBA
01/2024 - 07/2021
3LactamsIBA
01/2024 - 06/2021
3Linezolid (Zyvox)FDA Link
02/2023 - 08/2008
3ImmunosorbentsIBA
01/2023 - 11/2012
3Oxygen (Dioxygen)IBA
01/2023 - 01/2011
3Complement System Proteins (Complement)IBA
01/2023 - 01/2015

Therapy/Procedure

29Therapeutics
03/2024 - 03/2002
13Immunotherapy
01/2024 - 05/2011
7Artificial Respiration (Mechanical Ventilation)
01/2023 - 04/2008
6Resuscitation
01/2024 - 10/2006
6Ligation
05/2016 - 08/2003
5Precision Medicine
01/2024 - 01/2021
5Immunomodulation
11/2021 - 11/2008
4Critical Care (Surgical Intensive Care)
11/2022 - 09/2004
4Intravenous Administration
11/2008 - 03/2003